The Town of Poughkeepsie surrounds the City of Poughkeepsie on three sides. It is the Dutchess County’s most populous town with 42,000+ people. Visit the town of Poughkeepsie’s website. The Town is served by four different school districts including the Hyde Park Central School District on the north, the Arlington Central School District in the east, the Spackenkill Central School District just south of the City of Poughkeepsie and the Wappingers Central School District in the southern part of the Town. Just click on the school district name to be linked to its Web site. In all cases the mailing address is Poughkeepsie but the zip code might be 12601 or 12603. The Town of Poughkeepsie is home to a large IBM campus known for its ongoing development and manufacturing of IBM mainframes. Dutchess County’s two major shopping malls, Vassar College, Marist College, Dutchess Community College, St. Francis Hospital, and Bowdoin Park on the Hudson River are all located in the Town of Poughkeepsie. People living in this town can easily access commuter routes as well as the MTA Hudson line train stations in New Hamburg or the City of Poughkeepsie. Search Town of Poughkeepsie Real Estate.